May pomegranate flower flirtatious drying, green poplar with rain hanging heavy. Five-color new silk wrapped angle Zong, gold plate to send, raw gauze painting fan plate double phoenix.
It is bath orchid season move, Calamus wine U. S. Qing respect a total. In the leaves, a yellow Li when a get, still bleary, casual startled broken screen dream.
Ouyang Xiu
Time flies, it seems that peach blossoms have not Xie how long
Blink of an eye is already a brilliant pomegranate
The dragon boat festival holiday is coming
What are your travel plans for the holidays?
We’re still talking about the kidney transplant
Renal transplantation is the best alternative treatment for uremic patients
With the change of our citizens’ idea of organ donation, more and more citizens have the desire to donate organs after death.
This means that more patients with uremia can have a greater chance of an early new“Kidney” life.
Prior to receiving a kidney transplant, adequate knowledge of the kidney transplant is also essential.
Today, Dr. Zhu will talk to you about the most critical after kidney transplantation-rejection.
1. Why does rejection occur after kidney transplantation?
A: our body’s immune system is able to recognize and kill any“Foreign objects” that enter it, such as bacteria and viruses. This is known as immunity.
Unfortunately, however, the new kidney is also considered“Foreign” and is attacked by the immune system, a condition known as rejection. In the absence of effective treatment, such attacks can be fatal to a kidney transplant.
2. How do you know if rejection is occurring?
A: the symptoms of rejection are becoming less and less typical due to the use of powerful immunosuppressants, but be aware that rejection may occur if the following symptoms occur after a kidney transplant: And contact your kidney transplant doctor immediately:
Pain in renal allograft area, stiffening and enlargement of allograft;
Fever, body temperature above 38 °C and no obvious symptoms of infection;
A sudden decrease in urine output;
Sudden weight gain;
Swelling of hands and feet;
Elevated blood pressure.
3. Without feeling any discomfort, is it certain that no rejection has occurred?
A: No.
As mentioned in the previous question, rejection is becoming more and more atypical. Most rejections do not have obvious symptoms at the beginning, and routine tests can only show an increase in serum creatinine, even in a subset of patients with normal creatinine levels, renal biopsy results indicate rejection, and medications may need to be adjusted based on pathologic findings.
For your safety, regular follow-up after kidney transplantation is essential.
4. What are the types of rejection?
Answer: rejection can be divided into different types according to different principles, and its mechanism mainly includes two aspects of cellular immunity and humoral immunity.
The most common acute rejection is mainly mediated by cellular immunity, while hyperacute rejection and chronic rejection are mainly mediated by humoral immunity.
However, rejection is often cellular rejection and humoral rejection of the joint participation, it is difficult to completely distinguish between the two, clinical diagnosis is generally based on the main conclusion of the participation.
5. When does rejection occur after a kidney transplant?
A: rejection can occur at any time after kidney transplantation.
The incidence of acute rejection is usually highest in the first 6 months, especially in the first 3 months, and then decreases. However, acute rejection can occur even long after transplantation.
Chronic rejection generally occurs six months to a year after kidney transplantation.
6. Is it necessary to remove some of the precious glomeruli during a biopsy of a transplanted kidney?
A: we can assure you that a needle biopsy of a kidney transplant is necessary.
Each kidney has about 1 million glomeruli, and we only get about 10 to 20 glomeruli per biopsy, so there’s no need to worry about glomeruli.
Renal biopsy does have certain risks, such as bleeding, but the rate is very low, and there have never been significant complications from renal biopsy in our transplant center.
Most importantly, biopsy pathology can distinguish the diagnosis of rejection and drug toxicity, and can clarify the type of rejection. The results are directly related to the follow-up treatment plan, but also related to the recovery of the transplanted kidney, therefore, it is not necessary to reject a renal allograft biopsy for fear of complications.
The kidney transplantation center of Zhongshan Hospital affiliated to Fudan University has a long history of kidney transplantation and successfully performed the first kidney transplantation in children with Denys DRASH syndrome in China, together with the Shanghai China Soong Ching Ling Foundation, we have set up the“New kidney” charity fund to provide charitable assistance to the families of kidney transplant patients who are in financial difficulty.
We will join hands with you to relieve the suffering of uremia patients.
Wen | Zhu Dong, editor | Zhu Dong
This article is an original article of”Kidney Transplantation, sun yat-sen hospital, Fudan University”. It is reproduced with the author’s permission. To start with, you can also check out“Living donor kidney transplant, a gift of life” by clicking on [ read the original ] .
