Relative kidney transplantation is a way to greatly improve the success rate and survival rate of kidney transplantation, but finding a kidney that matches the recipient still needs to overcome the difficulties of human immunity, one of them, General who guards the pass, is our main character today, HLA. HLA, or Human Leukocyte Antigen, is a group of cell-surface antigens encoded by a complex of genes located in the Human chromosome 6 Human Leukocyte Antigen. It is also an important antigen that causes kidney transplant rejection
If the HLA match does not match, the recipient’s immune system may see the new kidney as a foreign invader and launch an attack.This is the transplant rejection. HLA-induced rejection mainly involves immune cell-mediated rejection and antibody-mediated rejection.
