Living related ABO-incompatible kidney transplantation
Code of Practice (2019 edition)
Until the problem of organ resources is fundamentally solved, expanding organ sources is an eternal theme in the field of organ transplantation. Kidney transplantation across the ABO blood group barrier can partially alleviate the shortage of kidney donors, bringing good news to long-waiting transplant recipients. Since December 2006, the number of routine ABO-incompatible kidney transplantation (ABOi-KT) has been increasing in our country.
1 selection of ABOi-KT recipients
Aboi-kt is suitable for patients with end-stage renal disease, and its indications and contraindications are basically the same as those of ABOc-KT.
1.1 indications
Aboi-kt is especially suitable for uremic patients who have difficulty finding ABO-compatible kidney sources in the short term, are poorly treated with dialysis, or have many life-threatening complications and can not receive other renal replacement therapies.
Indications include (1) various glomerulonephritis, (2) genetic disorder such as polycystic kidney disease, nephronophthisis, Eye-ear-kidney syndrome (Alport syndrome) , and (3) metabolic diseases, such as diabetes, hyperoxaluria, gout, porphyria, (4) obstructive nephropathy, (5) drug-induced kidney injury, (6) systemic diseases, such as systemic lupus erythematosus, vasculitis, progressive systemic sclerosis, etc. (7) hemolytic-uremic syndrome; (8) congenital diseases such as horseshoe kidney and congenital renal agenesis; (9) irreversible acute renal failure; (10) loss of both kidneys or solitary kidneys due to trauma.
